Drug Hunters. Exploring the Unexplored.

Delivering Novel Therapies for Cancer
and Other Serious Diseases

Orphagen is pioneering small molecule therapies to tackle cancer and other serious diseases. Our drug candidates block novel members of the nuclear receptor superfamily, a target class that has produced leading treatments for inflammation, oncology, and metabolic disease.Our first-in-class nuclear receptor programs, internally conceived and developed by us, are now on the path to preclinical and clinical development.

Our most advanced programs are directed in two areas:

  • a robust oncology program including both tumor-specific and precision therapy opportunities that encompass not only adrenal cancer but also head & neck and other squamous cancers.
  • a differentiated oral small molecule therapy for ulcerative colitis and Crohn’s disease

We talk actively with the investment, clinical, scientific, and patient communities to enable new kinds of therapy. Reach out to us for more information.

On a Mission to Imagine the Unimagined.

orphagen pharmaceuticals

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Orphagen Team

Our scientists and management team are committed to the best we can bring to bear in pursuit of new therapies. We are drug hunters. .

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Pipeline

Our mission is translational drug discovery and development with novel targets leading to first in class therapeutics.